Updated 4:24 p.m.
Wednesday afternoon, Charlotte Fire Marshall John Leonard said investigators determined an interior gas leak caused the explosion that leveled a home in the Ballantyne area of Charlotte.
Rania Karam, 58, was killed when her home on James Jack Lane exploded around 1:45 p.m. Her husband, Jebran Karam, a cardiologist practicing at Raleigh General Hospital in Beckley, West Virginia, was seriously injured in the explosion.
The fire department says it took rescuers about seven hours find Rania Karam in the debris.