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Of the 109 people currently listed as missing in South Dakota, 77 of them are indigenous. The state's legislature passed a bill this week to address the alarming crisis on and off reservations.

Hundreds of thousands of bikers are traveling to the Sturgis Motorcycle Rally in South Dakota again this year. Last year's rally was linked to several hundred cases.

Researchers surveyed commuters to find out what they do — and don't — get out of the daily trek to and from work. Many people say it's invaluable personal time to recover and switch gears.

Chris Ferrie's board books introduce subjects like rocket science, quantum physics and general relativity to toddlers and babies. What can parents do to make the concepts resonate?

Florida is among a growing number of states to ban gender-affirming care, such as puberty blockers or hormones, for transgender youth.

Many Democratic voters are lukewarm on Biden. Many Republican voters are lukewarm on Trump. As the dust settles from the midterms, we look ahead at what this means for the next big political contest.

A man who had a long-running dispute with his condo board in a Toronto suburb killed five people, including three board members, after he claimed the building's electrical room was making him sick.

Six former Mississippi Sheriff officers — some of whom called themselves "The Goon Squad" — plead guilty to state charges for the torture of two Black men.

A lot of medical equipment requires that patients stand or climb, activities that people with disabilities often can't do. As a result, people with disabilities sometimes skip routine exams or aren't examined properly.

For nearly twenty years, most air travelers in the U.S. have been required to remove their shoes when going through security. That requirement has ended.

After NPR reported on a Department of Homeland Security tool to check the citizenship of registered voters, three U.S. senators are expressing concern about accuracy, transparency and privacy.

The governor and top emergency official in Texas are both members of a council advising the Trump administration on options for eliminating the Federal Emergency Management Agency.

In his second term, President-elect Donald Trump is surrounding himself with people who can amplify his message and agree with how he wants to remake the executive branch.

Howard Bryant of ESPN.com and ESPN the magazine joins NPR's Scott Simon to talk about the MLB season winding down, and the wave of women in leadership in the NBA as the basketball season begins.

"I want to cause terror," the gunman behind Wednesday's deadly attack on a Dallas ICE immigration facility allegedly wrote in a note, according to authorities.

Bad Bunny returned to SNL as a host for the second time, and the musician addressed criticism over his upcoming Super Bowl performance.

Minnesota state and city leaders condemned the Trump administration's immigration crackdown in Minneapolis following Wednesday's fatal shooting of a 37-year-old woman by an ICE agent.

Nearly five-dozen water and septic system projects in 26 western counties will receive funding through the state Department of Environmental Quality.

Guan Heng sailed to the U.S. by boat from the Bahamas after publishing footage he filmed of purported detention camps in China. He has been held in immigration detention since August.

Hearings for President-elect Donald Trump's Cabinet nominees begin on Tuesday and ramp up on Wednesday. Here's what to look for.