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Amid an uproar over soaring drug prices, three GOP senators are seeking an investigation into whether the Orphan Drug Act is being manipulated to jack up the cost of medications for rare diseases.

For more than three decades, pharmaceutical companies have claimed a 50 percent tax credit for the cost of clinical trials of drugs for rare diseases. The credit is now in jeopardy.

Other House Freedom Caucus members have said that while they disagree with House Speaker Mike Johnson, they don't think it's in their best interests to go through another speakership fight.

NPR's Mary Louise Kelly speaks with former federal prosecutor Paul Rosenzweig, who is currently a Senior Fellow at the R Street Institute, about Robert Mueller's congressional testimony on Wednesday.

The finals of the 2024 Scripps National Spelling Bee kicked off Thursday night — and we caught up with some of the contestants before and after the event.

Alabama GOP Sen. Katie Britt and Texas Rep. Mónica De La Cruz delivered rebuttals to Biden's speech focusing on immigration, crime, inflation and national security.

While House Speaker John Boehner is almost certain to win re-election in his suburban Cincinnati district, his prospects of being re-elected as speaker are far less clear.

A vote in the House expected on Wednesday could end what is now the longest shutdown on record. Democrats are decrying the plan, saying it fails to address expiring health care subsidies.

Travis Scott has done a decent job shrouding his blatant co-opting of flows with gorgeous, synthy production. His latest single is no exception.

Dozens of workers have reportedly developed cancer and other afflictions at the world's largest chipmaker. The company stopped short of saying it directly caused the illnesses.

The National Transportation Safety Board says two children and the pilot were among those killed after a plane crashed en route from Chamberlain to Idaho. Three others were injured.

Oil surged past triple-digit prices for the first time since 2014. The breach of the psychologically significant milestone is bound to reinforce fears about inflation.

Austin's artful folk-rock duo provides an elegant but austere tale of triumph over heartbreak.

Kentucky Gov. Andy Beshear said all of the state's 120 counties were impacted by the storm. It also snarled travel at Charlotte Douglas International Airport in North Carolina. More than 100 flights were cancelled and another 300 were delayed, according to the website FlightAware.com.

State capitals around the country are dealing with security threats, and NPR's Scott Simon speaks to Kentucky's Gov. Andy Beshear about how his state is preparing for protests and unrest.

Nashville, Tenn., resident died of COVID-19 after being sent home from a hospital twice. Uninsured COVID-19 patients are rarely told their bills are covered by the government, an investigation shows.

Legendary crime writer Elmore Leonard published 46 novels, including Get Shorty and Out of Sight. His works were adapted countless times for film and TV. Noah Adams remembers the man whose advice to other writers was "try to leave out the part that readers tend to skip."

With the recent release of Steven Spielberg's Lincoln, the Civil War has been a hot topic. But for some people, like Rod Coddington, it's always an area of interest — blockbuster or not.

Most of the people Michael Croley's debut story collection feel like they don't belong, even in the places they call home — and Croley conjures that unsettled feeling in understated, beautiful prose.

The recruiting and vetting process already is under way for candidates who will run for Congress in 2014. For many candidates, part of that process involves hiring an investigator to look at their own background, as well as that of possible opponents. And there are even classes where you can learn how to do the digging.